2003～2005年永州市青少年学生乙肝感染动态分析

Dynamic analysis of hepatitis B virus infection among teen-aged students in Yongzhou City,2003-2005

目的分析近3年来乙肝病毒在不同类群青少年学生中的感染状况及动态变化。方法以酶联免疫吸附试验(ELISA)法,检测2003～2005年永州市参加中考、高考各类青少年学生共7605名的乙肝表面抗原(HBsAg)及“乙肝两对半”指标,参考其他因素和其他城市情况,逐年分组进行分析。结果3年HBsAg平均阳性率为11.65%,2003～2005年每年的HBsAg阳性率分别为10.20%、11.75%、13.36%,男女生阳性率分别为12.10%、10.28%,城乡学生阳性率分别为10.92%、13.16%,住校生、走读生阳性率分别为12.83%、11.15%,初、高中毕业生阳性率分别为10.88%、12.01%。886例HBsAg阳性学生中乙肝e抗原阳性者占61.52%。结论我市中青少年学生的乙肝感染率不但偏高,而且有不断增高趋势,其中传染性强的人群较大。农村学生、男生、住校生为乙肝重点感染人群,需给予特别关注。

Objective To understand the status of hepatitis B virus infection and its changes in various groups of teen-aged students in recent three years. Methods Enzyme linked immuncsorbent assay （ELISA） was used to detect HBsAg, HBsAb, HBeAg,HBeAb and HBcAb among 7 605 teen-aged students in Yongzhou City from 2003 to 2005, then the data were analyzed year by year. Results The HBsAg average positive rate was 11.65% during the three years, From 2003 to 2005, the HBsAg positive rates were 10.20%, 11.75% and 13.36% respectively. The HBsAg positiverates were 12, 10% and 10.28% in boy and girl students respectively, 10.92% and 13.16% in town and country students respectively, !2. 83 % and 11,15 % in boarding and nonboarding students respectively, and 10.88 % and 12,01% in junior and senior middle school students respectively. Among 886 HBsAg positive students, HBeAg positive rate was 61.52%. Conclusions Among teen-aged students, hepatitis B infection rate is not only high, but also increasing in Yongzhou City, and a number of them are strong infectious. Country students, boy students and boarding students should be paid a special attention.