充分认识风湿相关性疾病的眼表病变

Importance of recognition of ocular surface manifestation of rheumatic diseases

风湿相关性疾病的眼表损害包括干眼症、角膜边缘无菌性溃疡(溶解)、坏死性巩膜炎等。其发病机制与免疫复合物的介导有关。对于干眼症笔者给予人工泪液缓解症状,对角膜溃疡较浅的早期病例应用0.5%肝素及1%环孢霉素A或0.05%FK506点眼,对于角膜溃疡面较深,或接近穿孔、已穿孔者,可行板层或全层角膜、巩膜移植术。(眼科,2006,15:159-160)

The manifestations of rheumatic disease on ocular surface include dry eye, marginal nonbacterial corneal ulcer （corneal melting） and necrotizing scleritis. The pathogenesis involves with immune complex response. We use artificial tears to relief symptom in associated dry eye patients. For the superficial corneal ulcer we administer 0.5% heparin and 1% cyclosporin A or 0.05% FK506 topically to the eye, while for the deep corneal ulcer or tending to perforation or perforated, we employ lamellar keratoplasty or penetrating keratoplasty or sclera transplantation. （Ophthalmol CHN, 2006, 15：159-160 ）