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鼻咽癌多药耐药机制及其逆转的研究 被引量:1

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摘要 鼻咽癌的治疗方法是以放疗为主的综合治疗,化疗是治疗中晚期鼻咽癌的重要手段。肿瘤细胞对多种化疗药物产生耐药是造成化疗失败的主要原因。研究鼻咽癌的多药耐药及其临床逆转已成为亟待解决的问题。对鼻咽癌进行多药耐药研究,预测化疗的敏感性,进行个体化的治疗,对提高鼻咽癌的化疗效果。有重要意义。建立鼻咽癌耐药细胞系,筛查耐药相关基因,探讨耐药基因的作用机理,寻找逆转药物耐受的分子靶点具有重要的理论和实际意义。
出处 《中国医学文摘(耳鼻咽喉科学)》 2006年第5期299-301,共3页 Chinese Medical Digest(Otorhinolaryngology)
关键词 鼻咽肿瘤 药物疗法 抗药性 肿瘤 基因 MDR Nasopharyngeal Neoplasms Drug Therapy Drug Resistance, Neoplasm Genes, MDR
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