脉压对高血压患者左室结构的影响

Impact of office pulse pressure on left ventricular structure of patients with essential hypertension

目的：探讨诊所脉压（PP）对高血压患者左室结构的影响。方法：选择291例高血压患者（高血压组）和107例正常血压者（正常组）。所有入选者测量非同日3次诊所血压，并进行超声心动图检查。2组均根据PP水平：〈40mmHg（1mmHg=0．133kPa）、≥40～〈50mmHg、≥50～〈60mmHg、≥60mmHg分为A、B、C、D4个亚组。结果：高血压组左室质量指数（LVMI）随着PP增宽呈增大趋势，D亚组的LVMI为175．56±30．20；而在正常组中，不同亚组间LVMI差异无统计学意义。结论：PP升高是高血压患者左室肥厚及左室结构异常的重要危险因素。

Objective：To investigate the impact of office pulse pressure（PP） on left ventricular structure of patients with essential hypertension. Method： All subjects underwent the measurement blood pressure and echocardiography. Hypertension patients（n =291） were divided into 4 groups： group A：PP〈40 mmHg; groupB：40≤ PP%50 mmHg; group C：50≤PP%60 mmHg; group D：PP≥60 mmHg. Normal people（ n = 102） were also divided into 4 groups（A, B, C, D group） by the same method. Result：There was a position relation between PP and LVMI, EF in hypertension. PP was positively correlated to LVMI（ r = 0.21 ）. Conclusion： The increase of PP was an important risk factor of left ventricular structure abnormalities.