植物胞外钙调素与信号转导

Extracellular Calmodulin in Plants and Its Signaling Transduction Pathways

植物体需要构建复杂的信号转导体系以调节自身的生长发育过程并适应外界环境的变化,这种功能的实现需要胞内和胞外诸多信号分子的参与,胞外钙调素的发现使人们开始相信植物细胞外多肽信使的存在。胞外钙调素的生物学功能极其广泛,几乎涉及到植物生长发育的各个阶段,其信号转导途径是目前研究得最多也是最为清楚的方面,异三聚体G蛋白、磷脂酶C(PLC)-肌醇三磷酸(IP3)-肌醇三磷酸受体(IP3R)信号通路、活性氧和Ca2+通道之间直接或间接的相互作用是胞外钙调素信号转导的核心。

Complex signal transduction networks have been constructed in plants. They are necessary for plants to regulate their growth and developmental programs, and response to environmental cues. Many intracellular and extracellular signal molecules participate in the regulation of plants. People believed the existence of extracellular peptide signal molecules in plants since the discovery of extracellular calmodulin （CAM）. Because of the extensive biological functions, extracellular CAM participates in nearly all plant growth and development processes. We summarized recent findings, and then delineated extracellular CAM transmembrane and intracellular signaling transduction pathways. The direct or indirect relationships among heterotrimeric G proteins, PLC-IP3-IP3R signaling pathway, reactive oxygen species （ROS） and calcium channels, were the core contents of extracellular CaM signaling transduction.