克拉玛依市部分人群乙型肝炎病毒感染的血清学监测

SERUM SURVEILLANCE ON HEPATITIS B VIRUS(HBV) INFECTION AMONG POPULATIONS IN KARAMAY

目的:了解克拉玛依市部分人群乙型肝炎(乙肝)病毒(HBV)感染情况。方法:采用血清流行病学方法,随机抽样抽取3个行政区7类人群进行乙肝感染率的调查,检测乙肝病毒HBsAg、抗—HBs、抗-HBc、HbeAg和抗—Hbe。结果:人群中,学龄前儿童、幼儿教师接种乙肝疫苗(HepB)组与未接种组HBsAg差异无统计学意义(Р均>0·05),小学生、中学生、在职职工、退休职工及司机接种组HBsAg明显低于未接种组(Р均<0·01);人群中接种组单抗-HBs阳性率均明显高于未接种组(Р均<0·01)。人群中HBsAg和HBV总阳性率明显低于1990年调查结果(Р均<0·01);在职职工、退休职工及司机HBsAg和HBV阳性率均高于其它4类人群(Р均<0·01)。结论:克拉玛依市实施HepB接种14年后,有效控制了HBV的流行;该市还应加强非计划免疫人群的HepB接种,尤其应把特殊职业人群纳入HepB扩大免疫。

Objective： To know HBV infection status among population in Karamay. Methods： Obiective persons were chosen randomly in three districts of Karamay and HBV infection rate was investigated. Result： Difference was not statistically significant between inoculation group and non - inoculation group among children before being enrolled in school and kindergarten teachers （ P 〉 0.05）. Positive rate of HBsAg among primary school students, middle school students, employees, retirees and truckers of inoculation group were lower than that of non - inoculation group （P 〈 0.01 ） Difference was statistically significant between inoculation group and non- inoculation group among the other populations （P 〈 0.01 ）. Positive rate of HBsAg and HBV decreased obviously contrasting with year 1990 （P〈0.01）. Positive rate of HBsAg and HBV in employees, retirees and truckers were higher than that in the other populations （P〈0.01）. Conclusion： HBV infection has been controlled availably in Karamay after Hepatitis B inoculation was carried out for forteen years. Hepatitis B inoculation should be strengthed among the population besides EPI, especially the population engaging in special occupation.