脉压与心脑血管疾病危险因素的关系探讨

STUDY ON THE RELATIONSHIP BETWEEN PULSE PRESSURE AND RISK FACTORS OF CARDIO/CEREBROVASCULAR DISEASE

目的：了解人群脉压的分布特征及其与心血管病危险因素的关系。方法：对某医院2003-2004年体检者的血压、心率、血脂、血糖、血尿酸等资料进行描述，分析脉压与心血管疾病危险因素的关系。结果：本组人群平均脉压42．99mmHg，男女差异无统计学意义（P〉0．05）；随脉压增加，多种危险因素如体重指数、血压（收缩压、舒张压）、血糖、血脂（胆固醇、甘油三脂、低密度脂蛋白胆固醇）、血尿酸等均呈增加趋势（P〈0．001），收缩压增加的趋势强于舒张压；在较高的脉压水平，各种代谢性疾病如高脂血症、高尿酸血症、糖尿病等的检出率均增高（P〈0．001）。结论：脉压增大与多种代谢性疾病之间存在密切关联；脉压升高是心脑血管病的重要危险因素，应予以高度重视。

Objective to master the distribution characteristics of pulse pressure, and find out their relation with risk factors of cardio / cerebrovascular disease. Method： Situations about blood pressure, heart rate, blood lipids, blood glucose, uric acid of individuals who take physical check up in a hospital from 2003 to 2004 were described, and the relation among pulse pressure, types of hypertension and risk factors of cardio / cerebrovascular disease were analyzed. Result： The average pulse pressure of this group is 42.99 mmHg, no statistical difference between male and female （P〉0.05）. With the increase of pulse pressure, several risk factors such as body mass index, blood pressure, including systolic and diastolic pressure, blood glucose, blood lipids, including cholesterin, triglyceride and low- density lipoproteinemia cholesterin, uric acid and so on, raised （P 〈 0.001 ） . Systolic pressure increased higher than diastolic pressure. With higher pulse pressure, the detection rate of many metabolic diseases such as hyperlipidemia, hyperuricemia, diabetes, and so on, increased （P〈0.001） .Conclusion： There is a close relation between increased pulse pressure and types of metabolic disease. The increase of pulse pressure is one of the key risk factors of cardio / cerebrovascular disease, so the importance should be attached to it.