裂褶菌对小鼠抗疲劳作用的研究

Anti-fatigue Function of Schizophyllum commune in Mice

以裂褶菌子实体干粉(试验Ⅰ组和试验Ⅱ组)和裂褶菌发酵液(试验Ⅲ组)饲喂小鼠,检测裂褶菌子实体干粉和发酵液对小鼠肝糖原含量、肌糖原含量、琥珀酸脱氢酶(succinatedehydrogenase,SDH)活力、乳酸脱氢酶(lacticdehydrogenase,LDH)活力、血清尿素氮(bloodureanitrogen,BUN)含量及血乳酸(lacticacid,LD)含量的影响。结果表明,试验Ⅰ组、试验Ⅱ组和试验Ⅲ组小鼠的肝糖原含量、SDH活力及LDH活力极显著高于对照组(饲喂100%基础饲料)(p<0.01);试验Ⅰ组和试验Ⅱ组的肌糖原含量极显著高于对照组(P<0.01);运动后试验Ⅰ组、试验Ⅱ组和试验Ⅲ组小鼠的BUN增量和LD的水平极显著低于对照组(P<0.01),说明裂褶菌具有明显解除运动疲劳的作用。

Levels of liver and muscle glycogen, blood urea nitrogen （BUN）, blood lactic acid （LD）, succinate dehydrogenase （SDH） and lactate dehydrogenase （LDH） were determined in mice that were fed diets containing either Schizophyllum commune fruit body powder or submerged cultures of the fungus. Liver glycogen levels, and SDH and LDH levels in the serum of mice fed diets containing mushroom fruit bodies or submerged culture material were significantly higher （P〈0.01） compared with control mice fed basal feed only. Muscle glycogen levels were also significantly higher （P〈0.01） in mice fed fruit body-containing diets than in control mice. Compared with controls, LD elimination rates were higher, and increases in BUN were significantly lower （P〈0.01）, in mice fed diets containing either mushroom fruit bodies or submerged culture material. These data indicate a clear anti-fatigue function for S. commune.