乳腺恶性淋巴瘤10例病理分析

Pathologic Analysis of 10 Cases of Malignant Breast Lymphoma

本文报告10例乳腺恶性淋巴瘤,原发性7例,继发性3例。根据1985年成都会议修订非何杰金氏淋巴瘤分类标准,5例为核裂- 无核裂细胞性;1 例核裂细胞性;2 例无核裂细胞性;2 例淋巴浆细胞性。其中两例作过单克隆B细胞标记,结果1例κ阳性,κ阴性,另1例两者皆阴性。本组10例皆起源于B细胞。根据文献报道及本组病例无1例为乳腺何杰金氏淋巴瘤。讨论了乳腺髓样癌与无核裂性淋巴瘤鉴别;乳腺未分化癌与淋巴浆细胞性淋巴瘤、裂细胞性淋巴瘤鉴别及乳腺恶性淋巴瘤与乳腺假性淋巴瘤鉴别。认为术后和放疗后行多疗程联合治疗对其预后存活率有明显提高。

This article reports 10 cases of malignant lymphoma of the breast including 7 of primary and 3 of secondary. According to the stardard of classification which was revised at the meeting in Chendu in 1985, there were 5 cases of cleaved-noncleaved cell lymphoma, 1 of cleaved, 2 of lympho - plasmacytic and 2 of noncleaved. Monoclonal antibody marker study was performed in 2 cases, and as a result, one was K positive and λ negative, but in another case, K and λ were all negative. A differential diagnosis was discussed between noncleaved lymphoma and medullary carcinoma, undifferentiated carcinoma and lympho-plasmcytic lymphoma, undifferentiated carcinoma and lymphoplasmcytic lymphoma, and cleaved cell lymphoma, malignant lymphoma and pseudolymphoma of the breast. We consider that multiple sourses of combined chemotherapy after operation and irradiation might improve the prognosis and increase the survival rate.