国产α－氰基丙烯酸正丁酯栓塞治疗脑动静脉畸形

Endovascular embolization treatment of cerebral arteriovenous malformation with NBCA made in China.

目的探讨国产α－氰基丙烯酸正丁酯（ＮＢＣＡ）栓塞治疗脑动静脉畸形（ＡＶＭ）的适应证、技术要点、栓塞剂的配制及术后并发症。方法４０例病人应用微导管插管技术，在数字减影血管造影（ＤＳＡ）监视下，对畸形血管团进行血管内栓塞治疗。结果栓塞５７次，治愈８例，临床症状明显好转３１例，另１例死于其它疾病，无再出血病例。并发症主要为头痛、神经功能障碍及正常灌注压突破（ＮＰＰＢ），１例ＮＰＰＢ开颅清除血肿并切除畸形灶，１例视野缺损未恢复，其他经对症处理后均痊愈。结论ＮＢＣＡ血管内栓塞治疗脑ＡＶＭ是一种有效的治疗方法。国产ＮＢＣＡ性能良好，安全可靠，价格低廉，可代替进口产品。

bjective To research and discuss the indication of embolization,the characteristic of NBCA made in China, the catheterization technique,the technique note of embolization and the complications in the treatment of AVMs. Methods Using microcatheterization technique through endovascular approach under supervision of digital subtraction angiography (DSA), 40 case with AVMs were treated. Results Forty cases of AVMs were embolized in 57 times, 8 cases were cured, 31 cases had significant improvement of clinical symptoms and without rebleeding. Its complications included headache, neurological functional deficits, normal perfusion pressure breakthrough(NPPB).One case took place intracranial hemorrhage and was cured by surgical operation. One case had deficits of vision and didn't recover. Conclusions To treat AVMs by intravascular embolization with NBCA is a effective therapy method. NBCA made in China has a good characteristic, its price is lower and is a substitute of import product.