高血压对老年冠心病病人心脏事件的影响

The influence of hypertension on heart event in aged patients with coronary heart disease

随访２６５例老年冠心病和冠心病合并高血压病人２～８．５年，有４１例病人再发心脏事件，包括初发或再发急性心肌梗塞和心原性猝死。生存曲线分析表明，合并高血压冠心病病人的再发心脏事件率显著增高。Ｃｏｘ多元分析筛选冠心病和冠心病合并高血压两组病人的再发心脏事件的影响因素不同。结果提示高血压对心脏的损害可能是合并高血压的老年冠心病人预后更差的主要原因。

Two hundren and sixty-aged patients with CAD accompanied by hypertension were followed up for 2～8.5 years. During this period,recurrent heart events including acute myocardial infarction and sudden cardiac death occurred in 41 of these patients. The rate of recurrent heart events of the patients with CAD accompanied hypertension was significantly increased from an analysis of suvival curves. Cox proportional hazards regression analysis revealed that factors influencing reccurent heart events of the patients with CAD was different from that of the patients with CAD accompanied hypertension. The results indicates that the damage of hypertension to the heart appears to be the cause of poor prognosis of aged patients with CAD accompanied hypertension.