冲动性人格障碍和焦虑症患者视觉诱发电位的对照研究

The application researches on visual evoked potentials in impulsive personality disorder and anxiety neurosis

目的探讨冲动性人格障碍(IPD)和焦虑症(AN)在视觉诱发电位(VEP)中的特点。方法收集25例IPD组、33例AN组及52名正常成人对照(NC),以光刺激完成VEP检查。结果IPD组和AN组及NC组在潜伏期VEP/P1、P2、P3波幅VEP/N1-P2、P2-N2、P2、P3上差异有显著性(P<0.05或0.01)。与NC相比,IPD组潜伏期VEP/P1(68±16)ms、P2(160±10)ms前移,波幅VEP/N1-P2(18.4±3.2)μV、P3(5.6±2.4)μV增高,但波幅VEP/P2-N2(6.3±2.7)μV、P2(9.0±2.4)μV降低。与NC相比,AN组潜伏期VEP/P1(73±20)ms、P3(298±22)ms前移;波幅VEP/P2-N2(7.8±3.6)μV、P2(9.8±3.0)μV降低。IPD组与AN组相比,在潜伏期VEP/P2以及波幅VEP/N1-P2上两者差异有显著性,IPD前移于AN,波幅增高。结论在VEP若干指标上,IPD组前移于AN组,波幅增高。

Objective To investigate the characteristics of visual evoked potentials（VEP） of patients with impulsive personality disorder （IPD） and anxiety neurosis （AN）. Methods 25 IPD patients, 33 AN patients and 52 normal controls were examined using an American Nicolet Instrument. Results Compared with the normal controls, IPD group showed shortened VEP/P1, P2 latencies, increased VEP/N1-P2, P3 amplitudes （ IPD and AN groups： 3.4 ± 1.0μV,2. 1 ± 1. 1μV, respectively, P〈0.05）, and decreased VEP/P2-N2 amplitudes; AN group also presented shortened VEP/P1, P3 latencies and decreased VEP/P2-N2, P2 amplitudes. A significant difference of evoked potentials between IPD group and AN group was found with the latency of VEP/P2 and the amplitude of VEP/N1-P2. Conclusion IPD patients showed shorter latency and higher amplitude than AN group. The characteristics of evoked potentials of IPD and AN patients deserve more intensive studying.