老年人周围动脉硬化影响因素的Logistics回归分析

Logistic Regression Analysis of Factors Associated with Peripheral Arteriosclerosis in the Elderly

目的 探讨老年人周围动脉硬化的影响因素。方法 分析114例住院患者周围动脉硬化的影响因素,先采用单因素分析．其结果有统计学意义的因素再进入分析模型进行多因素的logistics回归分析；单因素分析采用确切概率法、成组设计两样本比较的t检验或成组设计两样本比较的秩和检验；周围动脉硬化的影响因素的多因素分析采用logistics回归分析方法；数据库的建立和有关数据处理采用SPSS11．0统计软件。结果 颈动脉增厚的相关因素有下肢动脉增厚（OR=3．301．95％CI：1．292-8．431）、高血压史（OR=1．963，95％CI：1．085-3．551）；颈动脉斑块的相关因素有下肢动脉斑块（OR=4．753．95％CI：1．246-18．122）；下肢动脉增厚的相关因素有颈动脉增厚（OR=3．155，95％CI：1．175-8．472）。结论 老年人周围动脉硬化与高血压病史、年龄直接相关，与血糖升高、血脂异常间接有关，颈动脉增厚与斑块形成和下肢动脉增厚与斑块形成之间互有正相关，以下肢动脉斑块的发生率为高。

Objective To explore the related factors about peripheral arteriosclerosis in the elderly. Methods One hundred and fourteen hospitalization patients were recruited and univariate and multivariate logistic regression analyses were applied to this study. Chi-squared test, Fisher＇ s exact test, student t test and Mann-whitney U-test were used in single factor analysis. All these statistical analysis were performed by the SPSS 11. 0 program for windows. P-value less than 0. 05 was considered statistically significant. Results The correlation factors of carotid artery thickening included the thickening of lower extremity artery （ OR = 3.301, 95 % CI： 1.292 - 8.431） and hypertension history （ OR = 1 .963, 95% Cl ： 1.085 - 3.551） . Formation of carotid plaque was correlated with formation of plaque of lower extremity artery （ OR = 4.753, 95 % CI ： 1. 246 - 18.122）, while thickening of lower extremity artery was correlated with thickening of carotid artery （OR = 3.155, 95 % CI： 1.175 - 8.472）. Conclusions Peripheral arterial occlusive disease in the eldedy is directly related with hypertension history and age, and indirectly related with hyperglycemia and dyslipidemia. There is positive relation of artery thickening and formation of plaque between carotid artery and low extremity artery. And the incidence rate of lower extremity artery plaque is higher than any other artery.