内毒素体克大鼠皮肤和肠系膜微循环的同步观测

The Simultaneous Observation of Microcirculation in Skin and Mesentery of Rats during Endotoxic Shock

应用两型激光多普勒显微镜及两套摄像录像装置对内毒素休克大鼠皮肤和肠系膜微循环的动态改变进行观察比较,发现在内毒素休克过程中微血流紊乱是微循环较早的共同变化之一,大鼠皮肤和肠系膜细动脉在血管痉挛收缩和血流速度减慢上变化相对一致,而细静脉的口径及渗出变化方面差异较大。所以,依外周微循环推测内脏微循环变化时应慎重。

Two types of laser Dopplcr microscopes and two sets of television-recording systems were applied to observe and compare the dynamic changes of microcirculation in skin and mesentery of rats during endotoxic shock. The results showed that blood flow disturbances was one of the common phenomena in microcirculation at the early course of shock. Spasm of arteriolcs and decrease of blood velocity in both areas were relatively same changes. However, the changes in diameter and exudation in venule showed great differences.