上海市宝山区271例肺癌危险因素的病例对照研究

A Case-control Study on the Risk Factors for Lung Cancer in 271 Cases in Baoshan District of Shanghai

目的探讨原发性肺癌的危险因素。方法对宝山区271例原发性肺癌进行1∶1配对病例对照研究,通过条件Logistic回归单因素分析和多因素分析筛选主要危险因素。结果近10a内室内装修(OR=2.212、95%CI0.668～7.323)与原发性肺癌发生最为密切。工作环境中有害因素(OR=1.958)、生活压力(OR=1.8)、经常下厨(OR=1.534)、家族史(OR=1.478)、吸烟(OR=1.461)为原发性肺癌的危险因素。经常吃蔬菜(OR=0.314)是保护因素。结论近10a内室内装修、工作环境中有害因素、生活压力、经常下厨是原发性肺癌的危险因素。

Objective To study the risk factors for the lung cancer. Methods A case-control （1：1） study was conducted in 271 lung cancer cases and control in Baoshan district, and the primary risk factors for lung cancer was studied with conditional Logistic analysis. Results The results showed that the closest risk factor for lung cancer was the house decoration during the near past 10 years （OR=2.212, 95% CI： 0.668-7.323）. Moreover, the harmful factors for lung cancer included occupation （OR=1.958）, life pressure （OR=1.8） and working in kitchen frequently （OR=1.534）, family cancer history （OR=1.478）, and cigarette smoking （OR=1.461）. But eating vegetable regularly was the protective factor （OR=0.314）. Conclusions Indoor Decoration, working in harmful environment, the big pressure in life, working in kitchen frequently were risk factors for the lung cancer.