氧瓶燃烧-孔雀绿-磷钼酸铵-PEG光度法测定蒙诺

Determination of the Monopril in Oxygen-Flask Combustion by Spectrophotometry with Malachite Green-Ammonium Phosphomolybdate-PEG

为寻找测定福辛普利钠的简便而实用的方法，建立了经氧瓶燃烧后，用孔雀绿．磷钼酸铵-聚乙二醇显色光度法测定蒙诺片剂中福辛普利钠含量的方法．测定线性范围为含磷量在1×10^-6～5×10^-6g／50mL，相关系数R=0．9998．测定片剂中福辛普利钠的含量与标示量比较，相对误差≤±0．8%，相对标准偏差RSD=0．44％（n=7）．

In order to seek a simple and utility method for determination of the fosinopril, the method of determination of the fosinopril in Monopril tablets with combustion in oxygen-flask by spectrophotometry with malachite green-ammonium phosphomolybdate-PEG was established in this paper. The linear range was from 1 × 10^-6 -5 ×10^-6g/50mL （P）, R=0. 999 8. The relative error which content of determination of the fosinopril in Monopril tablets was compared with scalar of tablets was less than 10.8%, and the RSD was 0.44% （n=7）.