1Tascon RI,Vazquezholand J,Gutierrezmartin CB.The RTX holemolysins ApxI and ApxⅡare major virulence factor of the swine pathogen Actinobacillus pleuropneumoniae:evidence from mutation analysis[J].MolMicrobiol,1994,14:207-221.
2ChoiC,KwonD,MinK,et al.Detect ion and localizat ion of ApxⅠ,Ⅱ,andⅢ genes of Actinobacillus pleuropneumoniae in natural porcine pleuropneumonia by in situ hybridization[J].Vet Pathol,2001,38:390-395.
3Schaller A,Kuhn R,Kuhnert P,et al.Characterization of ApⅣ,a new RTX determinant of Actinobacillus pleuropmeumoniae[J].Microbiology,1999,145:2015-2016.
7Peter Kuhnert,Yvonne Schlatter,Joachim Frey.Characterization of the type Ⅰ secretion system of the RTX toxin ApxⅡ in "Actinobacillus porcitonsillarum"[J].Veterinary Microbiology,2005,107:225-232.
7Schaller A, Kuhn R, Kuhnert P, et aL Characterization of apxIVA, a new RTX determinant of Actionobacillus pleuropneumoniae [J]. Microbiology, 1999, 145:2105-2116.
8Boekema BK, Kamp EM, Smits MA, et al. Both Apxl and Apxll of Actinohacillus pleuropneumoniae serotype 1 are necessary for full virulence [J]. Veterinary Microbiology, 2004, 100 (1-2):17-23.
9Frey J.Virulence in Actinobacillus pleuropneumoniae and RTX toxins.Trends Microbiol,1995,3(7):257-261
10Bosse JT,Janson H,Sheehan BJ et al.Actinobacillus pleuropneumoniae:pathobiology and pathogenesis of infection.Microbes Infect,2002,4(2):225-235