肺腺鳞癌手术病例临床分析

Clinical analysis of surgically treated patients with adenosquamous carcinoma of the lung

背景与目的 肺腺鳞癌是一种少见的病理类型。本研究旨在探讨肺腺鳞癌的临床特点。方法 回顾性总结经手术切除、病理确诊的115例肺腺鳞癌的临床资料。结果 无症状病例占全组12．17％（14／115）。女性肺腺鳞癌患者中49岁以下者占19．44％（7／36）。支气管残端阳性者占14．04％。淋巴结转移度为37．51％。Ⅲ期病例占全组54．78%（63／115）。结论 年轻女性（49岁以下，尤其是30～39岁）肺腺鳞癌发病率较高。常规手术支气管残端阳性多见。淋巴结转移度高。

Background and objective Adenosquamous carcinoma of the lung is a rare pathologic type of lung cancer. The aim of this study is to explore the clinical features of adenosquamous carcinoma of the lung. Methods A total of 115 patients with adenosquamous carcinoma of the lung were retrospectively analysed, who were diagnosed by operation and pathology. Results Among the 36 female patients, 7 were under 49 years （19.44%）. There were 14 patients （12.17%） without any symptom and 16 patients had residual carcinoma at the resection margin （14.04%）. The degree of lymph node metastasis was 37.51%. The proportion of stage Ⅲ patients was 54.78%. Conclusion The incidence of adenosquamous carcinoma of the lung in young women （under 49 years, especially under 39 years） is rather high. The residual carcinoma at the resection margin often occurs after routine operation. The degree of lymph node metastasis is rather high.