复方醋酸棉酚片治疗子宫肌瘤临床研究

The Clinical Studies of Treating Hysteromyoma with Compound Acetic Acid Gossypol Tablats.

目的探讨复方醋酸棉酚片治疗子宫肌瘤的临床效果。方法将确定为子宫肌瘤的患者50例进行治疗口服复方醋酸棉酚片20mg,每天晚饭后服,连服3个月。于治疗前后均用B超监测子宫及肌瘤体积、血尿常规、肝功能、血糖、血脂、促卵泡素、黄体生成素、泌乳素、孕激素、雄激素等指标。结果患者在治疗期间均出现闭经,症状消失,子宫平均缩小54．66％(P＜0．01),子宫肌瘤平均缩小50．65％(P＜0．05),血红蛋白恢复正常,血糖及泌乳素较治疗前降低,其他监测指标均无明显改变。结论复方醋酸棉酚片治疗子宫肌瘤有一定效果,副作用小,是一种可行的保守治疗方法。

Objective To discuss the clinical effect on treating hysteromyoma with compound acetic acid gossypol tablets. Methods 50 patients who are diagnosed with hysteromyoma take compound acetic acid gossypol tablets 20mg after supper every day for 3 months. Then Monitor the size of uteruses and tumors of the patients ,hemoglobinuria routine,liver function,blood sugar,blood ester,follicle stimulating hormone ,luteinizing hormone ,lactation hormone ,progestogen hormone,androsterone hormone using B -ultrasound waves before and after treatment. Results patients will have amenorrhea during treatment and the symptom will disappear. The tumor will dwindle in size by 54.66% （ P 〈 0.01 ） on average. The Hysteromyoma will dwindle by 50.66% （ P 〈 0.05 ） on average. Also hemoglobin, Hb returns to nomal. As a result,the blood sugar and lactation harmone reduce a lot than that before treatment. And other monitoring quality doesnt change obviously. Conclusions There is of great effect using compound acetic acid gossypol tablets to treat hysteromyoma and it has no side effect. It is an available conservative treatment.