胃癌手术后多因素分析及其临床意义

Multifactor Analysis in Postoperative Gastric Carcinoma

借助电子计算机对一组胃癌手术后病人的临床及病理资料进行多因素相关分析。结果发现,各种影响预后的因素之间存在着较广泛的相关关系;手术方式、临床病理分期,病理组织类型、并发症、年龄、术前化疗和性别等7项与术后生存期密切相关。经逐步回归分析筛选出其中5项因素建立一回归方程,分别为手术方式、临床病理分期、病理组织学类型、术前并发症和年龄。多因素分析方法用来探讨影响胃癌预后因素,能在较复杂的因素中筛选出最重要的因素及其组合,为临床诊治研究重点提供依据;通过逐步回归方程,可对具体病人术后生存期进行初步估计;为选择适宜合理的术后治疗方案提供指导。

A series of clinical and pathological materials of patients with gastric carcinoma were assessed with multivariant analysis by computer. The results showed, there weve manifold relationships among many factors influencing the prognosis of the patient. Seven factors were closely related to the postoperative survival time, i. e. operative method, clinical-pathological stage, histopathological type, complication, age, preoperative chemotherapy, and sex. Using stepwise regressive multivariant analysis, a regressive equation with five factors, i. e. operative method, clinical pathological stage, histopathological type, preoperative complication and age were established. The method of multifactors analysis and the stepwise regressive multivariant analysis may be used to select out the important factors influencing the prognosis and guiding the postoperative therapy and clinical research.