彩色超声对颈动脉粥样硬化斑块稳定性检查及内科治疗评价

Examination about stability of carotid atherosclerotic plaque by color ulrasound imagin and evaluation of treatment with medicine

目的探讨彩色超声对颈动脉粥样硬化斑块稳定性的检查,并进行内科干预治疗的临床评价。方法将150例伴有颈动脉粥样硬化斑块的急性缺血性脑血管病患者随机分为治疗组与对照组,根据超声检查斑块的特点评价为不稳定性或稳定性斑块,并测量颈总动脉内膜-中膜厚度(IMT),对照组给予盐酸氟桂利嗪(5mg/d)、复方丹参、维生素C,治疗组在此基础上加用氟伐他汀(40mg/d),阿司匹林(150mg/d),观察两组疗效。结果治疗组治疗1个月、3个月后颈总动脉IMT较发病初以及与对照组比较明显减小,颈动脉斑块趋于稳定。结论通过颈动脉超声检查可判断颈动脉斑块的稳定性;氟伐他汀和阿司匹林治疗具有改善颈动脉粥样硬化硬化、稳定斑块的作用。

Objective To explore the examination methods about stability of carotid atherosclerotic plaque and evaluate the curative effect of medicine on carotid atherosclerosis. Methods 150 patients with carotid atherosclerotic plaque in acute stage ischemic stroke were divided into treatment group and control group at random. Stable or instable plaques were assessed and carotid artery intima-media thickness（IMT） were measured according to the characteristics Of carotid atherosclerotic plaque on supersound imagin. The treatment in treatment group were different from that in control group. The therapeutic efficacy was observed respectively. Results After the treatment 1 month and 3 months, in treatment group carotid artery IMT decreaced more than that at accidence of treatment group and that of control group, the carotid atherosclerotic plaques stabilizese increasingly. Conclusion The stability of carotid atherosclerotic plaque may be evaluated through the ultrasound imagin. Statin and aspirin can lighten carotid atherosclerosis and stabilize the plaque.