腔隙性脑梗死112例临床特点及预后分析

Clinic characteristics and prognosis on lacunar cerebra infarction of 112 cases

目的总结腔隙性脑梗死的临床特点。方法选择112例腔隙性脑梗死病例资料进行回顾性分析。结果约40%患者有轻微症状,25%患者无临床症状体征,只在脑CT或核磁共振(MRI)影像上有病变显示。65%的患者为多发性腔隙性脑梗死,112例患者累计病灶219个。再发者76例,其中46%患者发展为痴呆、语言障碍、双侧瘫。结论腔隙性脑梗死患者症状体征大都较轻,其临床表现多样化;再发者比率高;再发后随其梗塞灶的增多,出现认知障碍和其他功能异常加重,远期预后不佳。

Objective To investigate clinic characteristics and prognosis of lacunar cerebra infarction. Methods 112 patients with lacunar cerebra infarction were selected and analyzed retrospectively. Results 40% of patients had slight symptom, symptom-free 25 % of patients was observed by the infarct sign based on the CT brain scan or MRI,65 % of patients was the frequency of cerebra infarction,infarct focus was 219 in the 112 cases, recrudescence in 76 patients including 35 patients（46% ） with symptom of dementia,language barrier and diplegia. Conclusions Clinic symptom of patients with lacunar cerebra infarction is slight, whereas clinic characteristics are variegated. Recrudescence rate is highter in patients with a previous history of the lacunarr cerebra infraction, and prognosis is bad. With the number of infarct focus increasing, clinic symptom of cognize obstacle and other function abnormity become more serious. This results may help clinicians to assess prognosis more accurately.