摘要
１９只猫随机分成Ａ组和Ｂ组。Ａ组７只接受全胰腺点状注射酒精，Ｂ组１２只经主胰管插管注射酒精，并将导管留在主胰管内造成主胰管部分梗阻，再全胰腺点状注射酒精。结果：术后全部实验猫均发生急性坏死性胰腺炎（ＡＮＰ）。Ａ组２只猎（２８．６％）在４８小时内死亡，５只猫术后６周胰腺组织形态和外分泌功能基本恢复正常。Ｂ组死亡４只（占３３．３％），其中３只在术后４８小时内死亡，另１只在术后２周死亡。其余８只猫术后１５周全部发展成慢性胰腺炎。由此提示单纯胰腺坏死可在致病因去除后得到恢复；如果致病因继续起作用．可造成组织学和功能方面的不可逆损害，最终可能发展成慢性胰腺炎。
Nineteen cats were randomly divided into two groups,7 cats (group A)recieved about 200 times spotty injections of total of 2 ml of 94% alcohol in pancreatic parenchyma and 12 cats(group B) underwent intraductal alcohol,partial obstruction of the main pancreatic duct(MPD) and intraparenchymal alcohol. Acute necrotizing pancreatitis occurred in all of the experimental cats after operation.2 cats in group A(28.6%) died within 48 hours postoperatively.4 cats in group B(33.3%)died,among them,3 within 48 hours and I died after 2 weeks. Morphological and functional recovery of the exocrine pancreas were found in all the 5 survivals in group A,while 8 cats in group B developed chronic pancreatitis 15 weeks after the operation.The above results show that simple pancreatic necrosis can be recovered after eliminating the etiological factors and if these factors,whatever is primary or secondary still exist and continue to damage the pancreas,chronic pancreatitis may develop.
关键词
胰腺坏死
胰腺炎
胰腺外分泌功能
Pancreatic necrosis Acute necrotizing pancreatitis Chronic pancreatitis Exocrine pancreatic function
