胰管引流治疗犬出血坏死性胰腺炎的实验研究

EXPERIMENTAL STUDY ON PANCREATIC DRAINAGE IN ACUTE HEMORRHAGIC NECROTIZING PANCREATITIS OF DOGS

采用逆行加压胰管注射犬自身胆汁建立急性出血坏死性胰腺炎（ＡＨＮＰ）模型，并应用经十二指肠切开，胰管内放置引流治疗。结果表明：本方法治疗ＡＨＮＰ可提高实验犬的生存率，降低死亡率保持胰管引流通畅可减轻实验大胰腺的病理变化，促进其修复。对临床治疗有指导意义。

The model of acute hemorrhagic necrotizing pancreatitis(AHNP) was produced by retrograde forced injection of autogenous bile Into the main pancreatic duct. The result showed that urgent surgical(transduodenal) intra-pancreatic duct drainage reduced the mortality rate of the experimental animals. Keeping the drainage patent and clear can both abate the pathological changes and promote the renovation of the dogs pancreas. So it can guide the clinical treatment in some way.