摘要
选用纯酒精单用或联合抗癌药治疗原发性肝癌患者５３例，经２个疗程后，完全缓解１６例，部分缓解２１例，总有效率６９．８％，中位生存期１０．１个月。３种不同治疗方案中纯酒精联合阿霉素方案有效率较高（７８．６％），毒副反应主要为消化道反应及肝功能损害，但低于纯酒精联合多种抗癌药方案，故认为此方案在对不适合手术或不接受手术治疗的肝癌患者，可作为一种补救方法。
During the past 42 months,a total of 53 patients with primary hepatic carcinoma(PHC) had been treated by fine needle percutanous ethanol intratumor infiltration(group P)and ethanol infiltration combined with intrahepatoportal chemotherapy around carcinoma, using adriamycin (group PA)or using adriamycin,carboplytin mitomycin and 5-Fu (group PC)for two courses. Result showed that 16cases were complete remission and 21 cases were part remission. The overall response rate was 69. 8%,with a median survival duration of 10. 1 months. After clinical contrast among three groups,the response rate in PA group exceeded P and PC group and adverse reactions was lower than PC group. The authors belive that this method might be a remedial measure for patients who are unsuitable for major surgery.
关键词
纯酒精
抗癌药
肝癌
治疗
Ethanol Antineoplasm drug Primary hepatic carcinoma
