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脑出血血肿周围水肿的病理生理研究 被引量：2

Pathophysiological Study of Peripheral Edema of Hematoncus in Patients with Cerebral Hemorrhage
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摘要 脑出血后血肿周围水肿的机制还不十分清楚。大量的研究表明,血液成分(溶解的红细胞、血浆蛋白的渗出、活化的血小板)血肿周围局部血流量的减少、脑出血后的炎性反应和凝血酶均和脑出血血肿周围水肿的形成有关。 The mechanism about periphefial edema of cerebral hematoncus is not very clear. Many studys showed that its formation was associated with many aspects including blood components （lysed red blood cells, exudation of plasma protein, activated platelet）,decreased regional cerebral blood flow around hematoma,inflammatory reaction after ICH and thrombin.
作者 高慧娟 黄永勤 李新毅
机构地区 山西稷山县人民医院神经内科 山西医科大学第一医院神经内科
出处 《医学综述》 2006年第19期1170-1173,共4页 Medical Recapitulate
关键词 脑出血 脑水肿 溶解的红细胞 血浆蛋白的渗出 活化的血小板 局部脑血流量 炎性反应 凝血酶 Intracerebral hemorrhage Brain edema lysed red blood cells Exudation of plasma pro-tein Activated platelet Regional cerebral blood flow Inflamraatory reaction after ICH Thrombin
分类号 R743.34 [医药卫生—神经病学与精神病学]
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参考文献19

  • 1Xi G,Keep RF,Hoff JT.Erythrocytes and delayed brain edema formation following intracerebral hemorrhage in rats[J].J Neurosurg,1998,89(6):991-996.
  • 2Bhasin RR,Xi G,Hua Y,et al.Experimental intracerebral hemorrhage:effect of lysed erythrocytes on brain edeme and blood -brain barrier permeability[J].Acta Neurochinir Suppl,2002,81:249-251.
  • 3Xi G,Hua Y,Bhasin RR,et al.Mechanisms of edema formation after intracerebral hemorrhage:effects of extravasated red blood cells on blood flow and blood-brain barrier integrity[J].Stroke,2001,32(12):2932-2938.
  • 4Wagner KR,XI G,Hua Y,et al.Clot retraction contributes to early Perihemotomal edema volumes following Intracerebral hemorrhage[J].Soc Neurosci,1997,23(7):1921.
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  • 7刘庆新,张苏明.高血压脑出血患者血小板CD62p和CD42b的表达及其与脑水肿形成的关系[J].中华急诊医学杂志,2004,13(3):186-188. 被引量：18
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二级参考文献6

  • 1Dardik R, Savion N, Kaufmann Y, et al. Thrombin promotes plateletmediated melanon cell adhesion to endothelial cells under flow conditions:role of platelet glycoproteins p - selectin and Gpllb - Ⅲlia. Br J Cancer,1998, 77: 2069-2075.
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  • 3Denis CV. Molecular and cellular biology of Von Willebrand factor. Int J Hematol, 2002, 37: 3 - 8.
  • 4Siddique MS, Femandes HM, Arene NU, et al. Changes in cerebral blood flow as measured by HMPAO SPECT in patients following spontaneous intracerebral hemorrhage. Acta Neurochir Suppl, 2000, 75: 517-520.
  • 5Song EC, Chu K, Jeong SW, et al. Hyperglycemia exacerbates brain edema and perihematomal cell death after intracerebral hemorrhage.Stroke, 2003, 34: 2215-2220.
  • 6方圻,王钟林,宁田海,邵耕,陈在嘉,陆宗良,李健斋,林传骧,周北凡,诸骏仁,诸永康,陶萍,陶寿淇,龚兰生,顾复生,游凯,戴玉华.血脂异常防治建议[J].中华心血管病杂志,1997,25(3):169-175. 被引量：3067

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医学综述
2006年 第19期

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