泌尿生殖道支原体感染及其药敏分析

Detection of mycoplasma caused infection and their antibiotic susceptibility

目的了解本地区泌尿生殖道支原体感染及药敏情况。方法采用珠海丽珠试剂厂出品ICS试剂盒进行检测和药敏试验。结果1811例标本中泌尿生殖道支原体感染567例,阳性率31.3%,其中男性14.1%,女性48.8%,女性阳性率明显高于男性(P<0.05)。Uu阳性率26.1%,Mh阳性率0.5%,Uu+Mh混合感染阳性率4.7%。支原体对9种抗生素的敏感率由高至低依次是美满霉素(72.6%)、强力霉素(72.2%)、克拉霉素(67.4%)、左氧氟沙星(45.7%)、氧氟沙星(41.8%)、司帕沙星(41.8%)、交沙霉素(24.7%)、阿奇霉素(17.6%)、罗红霉素(4.3%)。结论泌尿生殖道支原体感染率高,以Uu为主,女性明显高于男性;对支原体敏感性最高的美满霉素也仅接近73%,耐药性严重,罗红霉素已产生很高耐药性,对支原体治疗已基本无效,Uu+Mh混合感染增强了耐药性,对泌尿生殖道支原体感染者,应做支原体培养及药敏试验,以确定治疗方案。

[Objection] To find out the Mycoplasma infection and the sensitivity of the drug to treat it. [Methods] Culture and test the sensitivity of 9 antimicrobial to Mycoplasma with ICS Kit of Zhuhai Lizhu. [Results] 567 was positive among the 1811 specimens, the positive rate was 31.3%. 14.1% in man and 48.8% in female were positive, it was higher on female,s than male＇s（P 〈0.5）. Uu was 26.1%（the hightest）; Mh is0.5%; Uu＋Mh was 4.7% in Mycoplasma infection. With the highest begining, the sensitive rats of 9 kinds of antimicrobial were： MIN（72.6%） DOX（72.2%） CLA（67.4%） LEV（45.7%） OFL（41.8%）SPA（41.8%） JOX（24.7%） AZI（17.6%） ROX（4.3%）. [Conclusion] The infection rat is very high and female is higher than male, Uu infection is prime. Resistance is serious, the most sensitive drug is MIN next 73%. The ROX is nothing for treating Mycoplasma. Uu and Mh infecting together strengthen the resistance. For the peaple infected by mycoplasma, we can be consider as a treating with a disk susceptibility test.