ABO血型与PHC患者HBV感染标记相关性研究

The Relationship Between ABO Blood Group and HBV Markers of PHC Patients

研究伴ＨＢＶ感染的ＰＨＣ４４５例乙型肝炎抗原抗体与ＡＢＯ血型的关系，结果表明：１．伴ＨＢＶ感染的ＰＨＣＡ型血者显著高于对照组（Ｐ＜０．０１）。２．ＰＨＣ患者中ＨＢｓＡｇ、抗－ＨＢｃ的阳性率均以Ａ型血显著高于对照组（Ｐ＜０．０５）。３．ＰＨＣ患者中ＨＢｓＡｇ与抗－ＨＢｃ均阳性模式Ａ型血者显著多于对照组，而Ｂ型血者显著少（Ｐ＜０．０５）；抗－ＨＢｅ与抗ＨＢｃ均阳性的ＰＨＣ中，亦为Ａ型血者显著多（Ｐ＜０．０５）。提示有ＨＢＶ感染的Ａ型血者罹患ＰＨＣ的倾向性最高；而有ＨＢＶＭ、ＨＢｓＡｇ、抗－ＨＢｃ的Ａ型血者则为ＰＨＣ的易感人群，其中以ＨＢｓＡｇ和抗－ＨＢｃ同时阳性或抗－ＨＢｅ和抗－ＨＢｃ同时阳性的感染模式更易发生ＰＨＣ；也提示ＰＨＣ、ＨＢＶ、Ａ型血三者之间存在某种密切的、复杂的联系，对ＰＨＣ的发生有协同作用。对上述人群应密切关注，定期复查，以期早诊早治。

The relationship between HBV markers and ABO blood group was studied in 455 cases of PHC with HBV infection.The results shoWed:1. Patients with blood group A of PHC with HBV infection were obviously more as compared with control group(P<0.01).2.Positive rate of H13sAg or anti-HBc in PHC of blood group A was apparently highter as compared with control group(P<0.05). 3.Both HBsAg and anti-HBc positive in PHC of blood group A was markedly higher as compared with control,but obviously lower in PHC with blood group B(P<0.05).In PHC with bath anti-HBe and anti-HBc positive in PHC Of blood group A was markedly higher as compared with control,but obviously loWer in PHC with blood group B(P<0.05).In PHC with both anti-HBe and anti-HBc POsitive,, the most patients belonged to blabs group A (P<0.05).It suggested that people in blood group A with HBV infection tend to have PHC. People in blood group A who had HBV markers HBsAg and anti-HBc were susceptible to having PHC.Those who had both HBsAg and anti-HBc or anti-HBe and anti-HBc positive were the most susceptible to having PHC.There was a clOse and complex relationship among PHC, HBV and blood group A.They have collusive function in PHC.These people Should be paid more attention to follow up in order to have early diagnosis and early treatment.