卡波氏肉瘤及其病因分析

Analysis of the Pathogenesis about Kaposi's Sarcoma

卡波氏肉瘤是一种软组织多发性色素性血管肉瘤,根据本病临床表现、生物行为等特点分为四型。其致病原因目前尚无定论,目前主要有感染因子、免疫缺陷、遗传因子和细胞因子紊乱等学说。其中,人类8型疱疹病毒在KS发病中的作用受到了广泛重视。

Kaposi＇s Sarcoma（KS） is a multiple malignant idiopathic pigmented sarcomas. According to the character of clinical situation and biology behavior, it can be classified：Classic KS（CKS）,AIDS Associated KS（AIDS-KS）,endemic KS and immunosuppression-associated/transplantation-associated KS. Human Herpesivirus-8（HHV-8） is regarded as an important pathogenicity of KS. Moreover some scientists think that there are some relationship between KS and the disorder of cytokine or hereditary factors, but it is not sure about the exact pathogenesis of KS.