漏斗胸发病机制研究进展

Research Progress about Pathogenesis of Pectus Excavatum

漏斗胸是一种最常见的胸廓畸形,经过多年的发展,其手术矫形效果明显提高,但其发病机制众说纷纭,如胸骨和肋软骨发育障碍、膈肌发育异常、呼吸道梗阻、骨碱性磷酸酶异常、微量元素异常、遗传因素等,还都没有定论。本文就漏斗胸的发病机制简要综述。

Pectus excavatum is a most common deformity of anterior chest wall. With the development of several years, the result of operation are execellent. But there is no agreement among many views of pathogenic mechanism of pectus excavatum, such as growth disturbance of sternum and costal cartilages, maldevelopment of the diaphragm, respiratory tract obstruction, abnormality of bone alkaline phosphatase and microelement, hereditary factor and so on. In this article, the pathogenic mechanism of pectus excavatum is summarized.