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原发性肾小球疾病38例病理诊断与临床分析

Analysis on Pathology and Clinical Diagnosis for 38 Cases of Primary Glomerulopathy
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摘要 作者报道38例原发性肾小球疾病肾活检病理诊断与临床诊断。38例中慢性肾小球肾炎16例,其光镜病理论断为系膜增殖性肾小球肾炎(MsPGN)7例,微小病变(MCD)3例,膜增殖性肾小球肾炎(MPGN)2例,局灶性肾小球硬化(FGS)3例,新日体性肾小球肾炎(CGN)1例。隐匿性肾小球疾病8例,其中MsPGN 5例,MCD,FGS及不能诊断各1例。肾病综合征7例,其中MCD3例,MsPGN、MPGN、FGS和终未期固缩肾(ESCK)各1例。其他临床诊断共7例,其中毛细血管内增殖性肾炎(PEGN)2例,MCD,CGN,CGN,ESCK,MPGN和MsPGN各1例。上述结果表明,病理诊断同临床诊断无固定性联系,但有倾向性联系。MsPGN共14例,有浮肿7例和蛋白尿10例中的8例经治疗后浮肿和蛋白尿消失,而血尿有7例仅3例消失。MCD共8例,有浮肿7例,蛋白尿5例,经治疗后均消失。由此说明MCD和MsPGN的浮肿及蛋白尿治效好,而MsPGN血尿疗效差。MPGN和FGS共9例,上述3项指标疗效均差。 This paper reports an analysis of pathology and clinical diagnosis for 38 cases of primary glomerulopathy. Among them 16 persons were diagnosed by light microscope(LM) examination as having chronic glomerulonephritis, 7 having mesangial proliferative glomerulonephritis (MsPGN),3 minimal changing disease (MCD), 2 membranous proli-ferative glomerulonephritis( MPGN) , 3 focal glomerulosderosis(FGS), and 1 crescentic glomerulonephritis(CGN). There were 8 cases of latent glomerulopathy(LGN), in which 5 were MsPGN, 1 MCD, 1 FGS, and 1 case was not diagnosed Nepbrotic syndrome was diagnosed clinically in 7 cases, in which 3 were MCD, 1 MsPGN, 1 MPGN.lFGS and 1 end stage contracted kidney (ESCK). Other clinical diagnosis were made in 7 cases, in which 1 MsPGN,! MPGN.1CGN, 1 MCD, 1 ESCK and 2 proliferative endocapillary glomerulonephritis(PEGN).The results mentioned above show that there is no fixed relation between the pathologic diagnosis and the clinical diagnosis, but some relations between them exist. In 8 cases of MCD, 5 had proteinuria, 7 had edema After treatment both proteinuria and edema disappeared None of them had hemoturia. In 14 cases of MsPGN 7 had edema which disappeared after treatment, and 10 had proteinuria which disappeared in 8 cases after treatment I n 7 cases of hemoturia 3 responded well to treatment It is shown that edema and proteinuria of MsPGN respond well to treatment ,but hemoturia did not . Nine cases of MPGN and FGS respondes poor with respect to proteinuria and hemoturia. Edema and proteinuria in one of the 2 cases of CGN disappeared, but the hemoturia remained.
机构地区 西京医院心肾科
出处 《第四军医大学学报》 1990年第3期204-206,共3页 Journal of the Fourth Military Medical University
关键词 肾小球病 活检 病理学 临床分析 biopsy, pathology, dimcal glomerulonephritis glomerulosclerosis, focal
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参考文献4

  • 1黎磊石,中华内科杂志,1987年,26卷,5期,299页
  • 2谢自敬,中华肾脏病杂志,1987年,3卷,1期,25页
  • 3方国祥,中华肾脏病杂志,1985年,1卷,2期,84页
  • 4王海燕,中华肾脏病杂志,1985年,1卷,4期,3页

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