中国人与澳大利亚人冠状动脉病变规律的对比研究

A comparison study of coronary lesion by angiography between Chinese and Australian

目的:探讨中国人与澳大利亚人冠状动脉病变规律的差异。方法:选择中国南京冠心病患者3 021例(男性占68.4%),澳大利亚悉尼同步入选3 230例患者(男性占67.5%),分别进行冠状动脉造影(CAG),比较冠状动脉病变的支数及部位。结果:①中国人CAG阳性率为69.4%,右冠状动脉优势型为85.2%,澳大利亚人CAG阳性率为75.5%(P<0.05),右冠状动脉优势型为82.9%。②两组冠状动脉病变主要累及的血管依次为左前降支(LAD)、右冠状动脉(RCA)、左回旋支(LCX)、左主干(LM),中国人与澳大利亚人3支病变分别为26.0%和31.9%(P<0.01)。③中国人男、女3支病变分别为29.8%和15.8%,澳大利亚人男、女3支病变分别为34.0%和26.2%,与中国人同性别比较,澳大利亚人男、女LM、RCA病变率均高(P<0.01)。结论:中国人与澳大利亚人冠状动脉病变依次累及LAD、RCA、LCX、LM;与中国人比较,澳大利亚冠心病患者冠状动脉病变程度重,而且男、女患者均重;与女性比较,两组的男性患者冠状动脉病变均较重。

Objective ：To study and compare coronary lesion by angiography between Chinese and Australian. Methods：3 021 Chinese patients from Nanjing and 3 230 Australian patients from Sydney , whom were suspected to have coronary heart disease （CHD）, were included for coronary angiography. The coronary lesion was evaluated by the number and location of coronary lesion. Results ： ① 69.4% patients were diagnosed with CHD in Chinese, and 75.5% in Australian（P 〈 0.05）. Right coronary dominance was 85.2% in Chinese, and 82.9% in Australian . ②The involved coronary arteries were left anterior descending branch （ LAD）, right coronary artery （ RCA ）, left circumflex branch （ LCX ） and left main coronary artery （LM） in a descending order. The incidences of three branch lesions in Chinese and Australian were 26.0% and 3 I. 9% respectively. ③ The incidences of three branch lesions male and remale were 29.8% and 15.8% in Chinese, 34.0% and LM and LAD lesions in Australian were higher than those 26.2% in Australian. The incidences of both of the same gender Chinese. Conclusion：Theinvolved coronary arteries were LAD, RCA, LCX and LM in a descending order. Compared to Chinese, both Australian male and female had severe coronary lesion. Male patience had more severe coronary lesion in both Chinese and Australian compared to female.