口腔正畸患者治疗前体液中乙肝标志物的检测

A SURVEY OF HEPATITIS B MARKERS IN PATIENT'S BODY FLUIDS BEFORE ORTHODONTIC TREATMENT

目的:探讨口腔正畸患者和医务工作人员在治疗过程中发生乙肝病毒交叉感染、医源性传播、职业性感染的可能性。方法:采用时间分辨免疫荧光法检测患者血液和唾液的乙肝标志物,并作统计学分析。结果:在1268例患者中,血液乙肝标志物大三阳13例,小三阳78例,阴性812例,具有HBsAb或HBeAb、HBcAb者365例。37例HBsAg阳性患者的唾液有33例检测出HBsAg阳性,二者有显著相关性(P<0.05)。结论:乙肝病毒急性感染或携带者其唾液中含有传染性的乙肝病毒,是正畸治疗发生交叉感染、医源性传播、职业性感染的重要原因。正畸治疗前应进行乙肝标志物的检测。

Objective：To investigate the possibility of cross infection ,iatrogenic transmission and occupational infection during orthodontic treatment. Methods：Hepatitis B markers in patients＇ blood and saliva were tested by time - resolved fluoroimmunoassay ,and statistic analyses were done. Results：Among 1268 patients,three major markers HBsAg,HBeAg,HBcAb were positive in 13 patiens, HbsAg,HbcAb,HbeAb were positive in 78 patiens,812 patients were negative.Only HBsAb, HBeAb or HBcAb was positive in 365 patients.In 37 patients whose HBsAg was positive in blood,HBsAg was also positive in saliva in 33 patients. There was significant correlation （P〈0.05）.Conclusion：Hepatits virus in patient＇s saliva is an important cause of cross infection, iatrogenic transmission and occupational infection during orthodontic treatment .It is necessary to test bepstitis B marker in patient before orthodontic treatment.