部分脾动脉栓塞术治疗肝硬化脾功能亢进的临床观察

Efficacy of Partial Splenic Embolization for Hypersplenia in Liver Cirrhosis

目的：探讨对肝硬化脾功能亢进患者行不同程度栓塞后的临床疗效。方法：选择43例肝炎后肝硬化牌功能亢进患者。A组17例，栓塞面积约40％～50％CB组26例，栓塞面积约70％～80％。采用Seldinger技术经右侧股动脉插管到脾动脉脾门处或脾中下极动脉用PVA微粒行部分脾动脉栓塞。并于术后3d、1周、2周、1个月、3个月、6个月、1年及两年复查血常规，以此评价两种不同栓塞程度治疗的效果。结果：术后白细胞、血小板均上升。B组的疗效优于A组，并有统计学意义。结论：部分脾动脉栓塞面积在70％～80％疗效较好，在病情允许下应加大栓塞面积，以稳定疗效。

Objective ： To probe into the clinical curative efficacy on patients suffering from hyperslenia in liver cirrhosis after being treated by different areas of embolization. Methods：43 cases of patients suffering from posthepatitic cirrhosis hypersplenia were chosen and divided into 2 groups. Group A had 17 cases;area of embolization was about 40 % - 50%. Group B had 26 cases;area of embolization was around 70%-80%. The catheter was inserted using Seldinger＇s technique into the arteries of middle or lower pole of spleen and PVA granules were used as embolic material. After 3 days, 1 week,2 weeks, 1 month, 3 months, 6 months, 1 year, 2 years the blood routime examination was carried out. Results： After operation leucocytes and thrombocytes both ascend. However, two kinds of curative effect of different extent remain divergence. Group B is superior to Group A on efficacy. Conclusion ： The curative effect of partial splenic embolization in 70 % -80 % is better. It is preferable to enlarge the area of embolization,if the patient＇s condition permits,in order to steady the efficacy.