医用微孔钛界面内锁性生物固定机理的实验研究

Experimental Studies on Interface Mechanism of Interlocking Attachment of Porous Titanium

微孔钛的特点是容许新生骨小梁组织直接长入其孔隙内,形成内锁性生物固定,达到人工关节长期稳定的目的。作者采用球形钛粉末和钛纤维,分别植入24只犬股骨内。孔径是0.24mm,孔隙度是40％～50％。3月后测得界面剪切强度是4.6±0.36 MPa,扫描电镜显示微孔内有新骨成分,光镜显示新生骨细胞,新骨长入深度为3 mm。界面剪切性能可以满足人体应力负荷需要。研究表明:钛纤维表面结构的稳定性优于球形钛粉末。微孔钛研制成人工关节,可预防假体松动,并有助于临床开展新业务。

The feature of porous titanium is that new bone trabecular tissuc could ingrow into its pores and produce interlocking attachment.The spherical TC_4,powder and titanium fiber were seperately implanted into the femurs of 24 dogs.The pore size of the samples was 0.24mm and their rates of porosity were 40％～50％.After 3 months,the interface shear strength examined by straight pulling test,was over 4.6±0.36 MPa.Scanning electron microscopy showed that there were new bone components in the porous layer.Light microscopy also revealedthat there were new bone lacumae and their pathways in it.The depth of the reforming bone was 3mm.Interface shear strength of the new bone in the porous layer might meet the need of load bearing Porous materials would prevent the artificial joint from loosening and thus help to develop a new service clinically.