急性特发性肺间质纤维化在影像学上的表现

Image Feature of HRCT in Acute Idiopathic Pulmonary Fibrosis

介绍急性特发性肺间质纤维化的临床表现与影像学特征,以便及早作出诊断和治疗。方法该组6例有完整的临床、实验室结果、胸片、高分辧率CT(HRCT)资料并与病理活检做对照,重点介绍该病在高分辨率CT上的表现。结果6例临床表现为咳嗽、气急、呼吸困难和低氧血征。胸片显示两肺有多发的斑片状影。高分辧率CT上的表现是:磨玻璃样影、网状影以及晚期的蜂窝样影等。病灶以中下肺、胸膜下分布为主。结论临床表现、实验室检查、影像学特征相结合,有助于作出急性特发性肺间质纤维化的诊断,一经病理证实,及时治疗,部分病例可获得好的结果。

Objective This article introduces the clinical findings and imaging appearances of acute idiopathic pulmonary fibrosis（AIPF） in order to make the correct diagnosis and give appropriate treatment.Methods The 6 cases all had complete clinical and laboratory data as well as a serial and high resolution CT（HRCT） findings correlated with lung operation results.Results These 6 cases all had cough, progressive dyspnea and hypoxemia. Chest films showed multiple patchy densities distributed in both lungs fields. On HRCT scans：ground glass densitie, reticular and honeycomb lung were seen in the lungs and so on.The lesion was distributed in median and inferior areas of lung, especially subpleural lung.Conclusions According to the manifestations of chest films and HRCT scans ,correlated with characteristic clinical symptoms and laboratory findings,once AIPF was proved by pathology ,patient should be treated immediately to get comparatively good prognosis.