摘要
用以化学键联结的DNA—VT树脂对大鼠进行全血灌流,观察该树脂的血液相容性,同时测定DNA-VT树脂的理化性质及体外吸附DNA抗体的能力。结果表明,DNA-VT树脂血液相容性良好,能有效清除DNA抗体,可望应用于临床治疗系统性红斑狠疮。
Chemical bond-linked DNA-VT adsorbent is used for hemoperfusion in rats. The blood compatibility of the adsorbent is investigated. And also, the physical properties and immunoadsorption capacity in vitro are determined. Results show that DNA-VT adsorbent is of good blood compatibility and high adsorption capacity of DNA antibodies.The adsorbent is hopeful for the clinical treatment of SLE.
出处
《第一军医大学学报》
CAS
CSCD
1990年第2期180-183,共4页
Journal of First Military Medical University
关键词
红斑狼疮
血液灌流
免疫吸附
SLE
hemoperfusion
immunoadsorption
DNA antibody, DNA-VT adsobent
blood compatibility
