摘要
结直肠癌易发生肝脏等器官的转移,有时肝脏是唯一的转移部位。手术治疗是结直肠癌肝转移的主要治疗手段,有些患者术后可以长期生存,但毕竟只有10%~20%的患者适合手术治疗。本文重点介绍如何通过化疗方案的改进或联合分子靶向治疗,将不可手术的结直肠癌肝转移病例转化为可手术切除的病例.或通过采用射频消融治疗等综合治疗手段提高疗效,达到长期生存或延长生存期。
Colorectal cancer has the propensity to develop liver-dominant metastases. In some of these patients, the liver is the only site of metastatic disease. Thus, surgical resection is the mainstay of treatment for liver-only eolorectal cancer metastases, which can produce long-term survival in selected patients, but only 10%-20% of patients are suitable for a surgical approach. In this paper we introduced how to transfer the inoperable coloreetal liver metastases to operable colorectal liver metastases through improved chemotherapy with /without molecular target therapy and multidisciplinary treatment approaches, and the results of radiofrequency ablation (RFA) , which can also produce long-term survival in a subset of patients with colorectal liver metastasis or prolong survival duration.
出处
《中国癌症杂志》
CAS
CSCD
2006年第10期781-784,共4页
China Oncology
关键词
结直肠癌
肝转移
综合治疗
化疗
射频治疗
coloreetal cancer
liver metastasis
multimodality treatment
chemotherapy
radiofrequency ablation