流量介导的肱动脉扩张和颈动脉内中膜厚度对冠心病患者发生心血管事件的预测作用

The value of flow mediated brachial artery dilation and carotid artery intima-media thickness in predicting cardiovascular events in patients with coronary artery disease

目的探讨流量介导的肱动脉扩张(FMD)和颈动脉内中膜厚度(IMT)能否预测冠心病患者心血管事件的发生。方法150例经冠状动脉造影明确患有冠心病的患者作为观察对象,分别测量每位患者的肱动脉FMD和颈动脉IMT,随访24个月,观察150例患者心血管事件的发生率,并比较心血管事件发生者与未发生者肱动脉FMD和颈动脉IMT的差别。结果150例患者中有21例在24个月的随访时间内发生心血管事件,未发生心血管事件者的肱动脉FMD较发生心血管事件者低,颈动脉IMT在未发生心血管事件者和发生心血管事件者中相差不显著(P>0.05)。结论肱动脉FMD可以帮助预测冠心病患者心血管事件的发生。

Objective The goal of this study was to detect whether brachial artery FMD and carotid artery IMT can play a role in predicting the cardiovascular events in coronary artery disease. Methods One hundred and fifty patients with coronary angiography diagnosis of CAD were selected, brachial artery FMD and carotid artery IMT were measured for the selected patients respectively. These patients were followed up for cardiovascular events for 24 months, brachial artery FMD and carotid artery IMT were compared in patients with cardiovascular events with those without cardiovascular events. Results During 24 months period, there were 21 cardiovascular events occurred in the 150 patients. Brachial artery FMD was lower in patients with cardiovascular events than those without cardiovascular events. There was no significant difference in carotid artery IMT of patients with cardiovascular events and those without cardiovascular events. Conclusion Brachial artery FMD is helpful in predicting cardiovascular events in coronary artery disease.