摘要
2001年荷兰学者van den Hoogen等首次在不明原因的呼吸道感染儿童中分离出一种新病毒，电子显微镜下呈现类似副黏病毒的多极丝状形态，生化特征亦与副黏病毒相似。之后许多学者对其基因组组成和序列进行分析，支持将其归类于单分子负链RNA目副黏病毒科肺病毒亚科偏肺病毒属，并命名为人类偏肺病毒（hMPV），成为偏肺病毒属的第1个人类病毒。根据遗传系统发生学分析和血清学抗体中和试验等将其分为2型4个亚型。本文就hMPV的病毒归类、分型、病毒繁殖特点及其发病及流行病学、临床表现、诊断、治疗和疫苗的研制进展综述如下。
出处
《微生物与感染》
2006年第3期174-176,183,共4页
Journal of Microbes and Infections
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