彩色多普勒超声在病理性瘢痕研究中的应用

The application of Color-Doppler Flow Imaging in the research for pathological scar

目的应用彩色多普勒超声观察不同病程的病理性瘢痕在浅表组织的血流声像、血流阻力上的差异,并与正常皮肤比较,探讨病理性瘢痕形成的原因。方法选取45例增生性瘢痕和20例瘢痕疙瘩的患者,并将其按瘢痕形成的时间分组,用彩色多普勒血流显像系统测量瘢痕一定范围内血管数目、血管阻力指数,用SPSS11.0软件进行对比分析。结果①增生性瘢痕、瘢痕疙瘩和正常皮肤的平均血管密度依次递减,平均动脉阻力指数依次递增。②随着病程的延长,增生性瘢痕的血管密度呈先增后减现象,动脉阻力指数逐渐增高,差异有显著意义(P<0.05);瘢痕疙瘩中各参数的变化,差异无显著意义(P>0.05)。结论随着病程的延长,增生性瘢痕血流声像与血流动力学有向正常皮肤恢复的趋势,而瘢痕疙瘩却无此趋势。

Objective Comparing with normal skin, to explore the etiopathogenesis of pathological scar forming by observing the differences of the ultrasound imaging of blood flow in superficial tissue and resistance of blood flow using the Color- Doppler Flow Imaging. Methods Forty- five cases of hypertrophic scar and 20 cases of keloid were chosen. Both of them were grouped according to the course of disease. The vessel number and resistance index in the same range of scars were measured by Color- Doppler Flow Imaging system, and the results were analyzed with SPSS 11.0. Results ① In hypertrophic scar, keloid and normal skin, the average vascular density has decreased one by one, and the average RI has increased one by one. ②In hypertrophic scar, the vascular density firstly increased thereafter decreased with the course of disease prolonged, the resistance index gradually increased, all the divergence were significant （P 〈 0.05）. But in keloid, the changes of these parameters weren＇t significant （ P 〉 0.05）. Conclusion Hypertrophic scars has a tendency of reverting to normal, but keloids haven＇t.