巴曲酶治疗进展性脑梗塞40例临床观察

Effects of batroxobin for progressive cerebral infarction

目的观察巴曲酶在进展性脑梗塞中的治疗作用。方法对40例进展性脑梗塞患者给予标准疗程的巴曲酶治疗,评定治疗前后的神经功能缺损评分、血液流变学指标及总体疗效。结果于治疗开始的第1、2、3、5、7、14 d分别有50%、75%、80%、90%、92.5%、92.5%患者的神经功能缺损评分明显改善,血液流变学指标也得到显著改善(P<0.05)。结论巴曲酶能改善、减轻进展性脑梗塞患者神经功能缺损程度和血液流变学,是治疗进展性卒中较理想的药物。

Objective To investigate effect of batroxobin for progressive cerebral infarction. Methods Standard courses of batroxobin were given for 40 patients with progressive cerebral infarction, scandinavian stroke scale, hemorheology and therapeutic effect were assessed before and after treatment. Results Scandinavian stroke scales were obviously improved about 50%, 75%, 80%,90%,92.5%,92.5% respectively after 1, 2, 3, 5, 7, 14 days; hemorheologys were also changed markedly（P〈0.05）. Conclusion Batroxobin can improve and alleviate neuronal deficits and hemorheology of patients with progressive cerebra infarction, it is a better ideal drug for ones.