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PTEN及其与前列腺癌关系的研究进展 被引量:2

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作者 沈静侠 姜达
出处 《实用肿瘤学杂志》 CAS 2006年第5期437-440,共4页 Practical Oncology Journal
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参考文献24

  • 1Li J,Yen C,Liaw D,et al.PTEN,a putative protein tyrosine phosphotase gene muted in human brain,breast and prostated cancer[J].Science,1997;275:1943-1947
  • 2Steck PA,Perhouse MA,Jasser SA,et al.Idenfication of a candidate tumor suppressor gene,MMAC1,at chromsome 10q 23.3 that is muted in advanced cancers[J].Nature Genet,1997;15:356-362
  • 3Li DM,Sun H.TEP1,encoded by a tumor suppressor locus,is a novel protein tyrosine phosphotase regulated by transforming growth factor beta[J].Cancer Res,1997;57:21242-21291
  • 4Wu Y.PTEN 2 a golgi2 associated testis specific homologue of the PTEN tumor suppressor lipid phosphatase[J].J Biol Chem,2001 ;276(24):21745
  • 5Dong XY.Identification of two novel CT antigens and their capacity to elicit antibody response in hepatocellular carcinoma patients[J].Br J Cancer,2003;89(2):291
  • 6Parsons R.Human cancer,PTEN and the PI23K kinase pathway[J].Semin Cell Dev Biol,2004; 15(2):171-176
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  • 9Frauke L,Kristin M,Anett S,et al.PKN3 is required for malignant prostate cell growth downstream of activated PI3-kinase[J].The EM-BO Jurnal,2004;23:3303-3313
  • 10Weng LP,Biown JL.Eng CIPTEN coordinates G(1) arrest by down-regulating cyclin D1 via its protein phosphatase activity and upregulating p27 via its lipid phosphatase activity in abreast cancer model[J].Hum Mol Genet,2001;10(6):559-604

同被引文献43

  • 1李艳,王新允,刘婷,朱丛中,孙翠云,王爱香,赵敏,吴兴业.肺癌及癌前病变组织芯片中PTEN的表达及其意义[J].肿瘤,2006,26(1):52-54. 被引量:3
  • 2夏雪雁,李连宏,李先承,姜涛.凋亡抑制基因Survivin和抑癌基因PTEN在前列腺癌组织中的表达及临床意义[J].中华男科学杂志,2006,12(4):346-348. 被引量:17
  • 3刘万涛,田大力,高英,智连艺.抑癌基因PTEN在小细胞肺癌中的表达及临床意义[J].中国医科大学学报,2006,35(1):65-66. 被引量:3
  • 4于文成,刘伟.非小细胞肺癌PTEN表达与细胞凋亡和增殖关系[J].青岛大学医学院学报,2007,43(1):8-11. 被引量:7
  • 5Gu J,Tamura M, Pankov R, et al. Shc and FAK differentially regulate cell motility and directionality modulated by PTEN [ J]. Cell Biol,1999,146(2) :389.
  • 6Zeng L,Si XU,Yu WP,et al. PTP regulates intergrin-stimulated FAK autophosphorylation and cytoskeletoal rearrangement incell spreading and migration [ J]. Cell Biol,2003,160( 1 ) : 137.
  • 7Gu J, Masahito T,Yamada KM. Tumor-suppressor FFEN inhibits integrin and growth factor mediated mitogen activated protein(MAP) kinases ignaling pathways [J]. Cell Biol, 1998,143 ( 5 ) : 1375.
  • 8Weng LP,Smith WM, Brown JL,et al. PTEN inhibits insulin-stimulated MEK/MAPK activation and cell growth by blocking IRS- 1 phosphorylation and IRS-1/Grb-2/Sos complex formation in a breast cancer model [ J ]. Hum Mol Genet,2001 , 10 ( 6 ) : 605.
  • 9Soria JC, Lee HY, Lee JI, et al. Lack of PTEN expression in non-small cell lung cancer could be related to promoter methylatlon [ J]. Clin Cancer Res,2002,8(5) :1178.
  • 10Kohno T,Takahashi M, Manda R, et al. Inactivation of the PTEN/ MMAC1/TEP1 gene in human lung cancers [ J]. Genes Chromosomes Cancer, 1998,22 (2) : 152.

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