参附注射液应用于心肺复苏过程中相关指标的变化

Study on the Nursing of Shenfu Injection on Multiple Organ Injuries in Patients after Cardiopulmonary Resuscitation

目的:观察在心肺复苏过程中应用参附注射液后相关指标的变化。方法:将我院40例经心肺复苏后自主循环建立>24小时的心跳骤停患者随机分为参附治疗组(A组)和常规复苏组(B组),观察即刻、4、24、48小时动脉血气变化,并观察复苏后4、12、24、48小时的平均动脉压及GCS评分的变化。结果:复苏后24、48小时酸中毒症状A组比B组明显减轻,差异显著(P<0.05)。复苏后各时段的平均动脉压A组明显高于B组,差异显著(P<0.05,P<0.01)。GCS评分48小时A组明显高于B组,差异显著(P<0.05)。结论:参附注射液具有强心、改善微循环、保持复苏后的血流动力学稳定、防止重要脏器的缺血-再灌注损伤的作用,在心肺复苏时应加强对相关护理指标的观察及分析。

Objective： To observe changes of related nursing index with Shenfu injection in patients after cardiopulmonary resuscitation （CPR）. Methods ：40 patients were randomly divided into 2 groups：Shenfu injection treatment group（ n = 24 ） and control group （n = 16） 24 hours after successful CPR,arterial blood gases of whom were analyzed instantly,4,24 and 48 hours later, and changes of MAP and GCS scores of whom were detected 4,12,24 and 48 hours later. Results ： Campared with control group, symptoms of acidosis in Shenfu injection treatment group were significantly slighter 24 and 48 hours later（P 〈 0.05 ） , MAP was significantly higher in all time points（ P 〈 0.05, P 〈 0.01 ） ,and GCS seores were significantly higher 48 hours later（ P 〈 0.05 ）. Conclusion ： Shenfu injection could strengthen contractility of myocardium,improve microcirculation,maintain stabilization of hemodycamics and avoid ischemia-reperfusion injury on vital organs after CPR. Nursing items of Shenfu injection should be enhanced after CPR.