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血清丙氨酸转氨酶正常的慢性丙型肝炎的治疗

Treatment in chronic hepatitis C patients with normal serum alanine aminotransferase
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摘要 丙型肝炎病毒(HCV)感染的流行较为广泛,呈全球性分布。慢性丙型肝炎患者如得不到及时和合理的治疗,可发展为肝硬化、肝细胞癌。对血清丙氨酸转氨酶(alanine aminotransferase,ALT)升高的慢性丙型肝炎患者的治疗早已取得共识,即应采取积极的抗病毒治疗;但对ALT正常的慢性丙型肝炎患者是否应该常规接受抗HCV治疗,长期以来一直存在分歧。本文对ALT正常的慢性丙型肝炎的流行病学、自然史和治疗等研究进展作简要的介绍。
出处 《中国感染与化疗杂志》 CAS 2006年第5期356-360,共5页 Chinese Journal of Infection and Chemotherapy
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参考文献25

  • 1Dufour DR,Lott JA,Nolte FS,et al.Diagnosis and monitoring of hepatic injury.I.Performance characteristics of laboratory tests[J].Clin Chem,2000,46:2027-2049.
  • 2Robert J,Pokorski.Hepatitis C Virus Infection in Japan[J].Risk Insights,2001,2:33-38.
  • 3Bacon BR.Treatment of patients with hepatitis C and normal serum aminotransferase levels[J].Hepatology,2002,36(5 Suppl):S179-S184.
  • 4Ahmed A,Keeffe EB.Chronic hepatitis C with normal aminotransferase levels[J].Gastroenterology,2004,126:1409-1415.
  • 5Puoti C,Castellacci R,Montagnese F,et al.Histological and virological features and follow-up of hepatitis C virus carriers with normal aminotransferase levels:the Italian prospective study of the asymptomatic C carriers (ISACC)[J].J Hepatol,2002,37:117-123.
  • 6刘玉振,邢培清,李伍升,方建华,温涛.无偿献血人群中ALT、抗-HCV和HBsAg阳性模式分布调查[J].解放军预防医学杂志,2004,22(4):278-279. 被引量:5
  • 7Shiffman ML,Stewart CA,Hofmann CM,et al.Chronic infection with hepatitis C virus in patients with elevated or persistently normal serum alanine aminotransferase levels:comparison of hepatic histology and response to interferon therapy[J].J Infect Dis,2000,182:1595-1601.
  • 8Pradat P,Alberti A,Poynard T,et al.Predictive value of ALT levels for histologic findings in chronic hepatitis C:a European collaborative study[J].Hepatology,2002,36:973-977.
  • 9Jamal MM,Soni A,Quinn PG,et al.Clinical features of hepatitis C-infected patients with persistently normal alanine transaminase levels in the Southwestern United States[J].Hepatology,1999,30:1307-1311.
  • 10Persico M,Persico E,Suozzo R,et al.Natural history of hepatitis C virus carriers with persistently normal aminotransferase levels[J].Gastroenterology,2000,118:760-764.

二级参考文献16

  • 1Camma C, Bruno S, Schepis F, et al. Retreatment with interferon plus ribavirin of chronic hepatitis C non- responders to interferon monotherapy: a meta- analysis of individual patient data[ J ]. Gut, 2002,51:864-869.
  • 2Papatheodoridis GV, Papadimitropoulos VC, Hsdziyannis SJ. Effect of interferon therapy on the development of hepatocellular carcinoma in patients with hepatitis C virus- reated cirrhosis: a meta- analysis[J] .Aliment Pnarmaool Ther, 2001,15:689- 698.
  • 3Kjaergard LL, Krogsgaard K, Gluud C. Interfern alfa with or without ribavirin for chronic hepatitis C: systematic review of randonmised trials[J].BMJ, 2001,323:1151 - 1155.
  • 4Alberti A, Benvegnu L. Management of hepatitis[J] .J Hepatol, 2003,38(Suppl1): S1014 - S1 18.
  • 5Poynard T, MdHutchison J, Davis GL, et al. Impact of interferon alfa - 2b and ribavirin on progression of liver fibrosiis in patients with chronic hepatitis C[J].Hepatology, 2000,32:1131 - 1137.
  • 6Booth JCL, O' Grady J, Neuberger J. Clinical guidelines on the mangement of hepatitis C[J]. Gut, 2001, 49(Suppl I ): il - i12.
  • 7Chander G, Sulkowski MS, Jenckes MW, et al. Treatment of chronic hepatitis C: a systemic review[J]. Hepatology, 2002, 36(5 Suppl 1 ):S135 - S144.
  • 8Di Ciomm no V, Russo P, Rava L, etal. Interferon alpha in the treatment of chronic hepatitis C in children: a mmeta- analysis[J] .J Viral Hepat,2003,10:210 - 214.
  • 9Fabrizi F, Dulai G, DixitV, et al. Meta- analysis: interfeorn for the treatment of chronic hepatitis C in dialysis patients[J] .Aliment Phamacol Ther, 2003,18:1071 - 1081.
  • 10National Institute of Health Consensus Development Conference Panel Statenent. Management of hepatitis C[J].Hepatology, 2002,36(5 Suppl 1):S3- S20.

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