急性白血病的心脏损害及参麦为主的防治作用

目的观察急性白血病(AL)患者心脏损害及参麦注射液为主防治的疗效。方法以心电图、血清心肌酶谱观察心脏损害。治疗组化疗期加用参麦注射液及辅酶Q10片,对照组仅出现心脏损害时加用辅酶Q10片,连用6个疗程。结果心脏损害发生率在103例初治AL患者中占39.8%,完全缓解(CR)中仅9.4%,6次化疗结束CR者中21.6%,其中治疗组中仅12.8%,对照组中31.4%,治疗组明显低于对照组。结论AL患者心脏损害发生率随疾病缓解下降,6次化疗后又有增加。参麦注射液为主防治AL心脏损害有效。

Objective To investigate the heart damage in acute leukemia （AL）, the prevention and treating effects mainly with shenmai. Methods ECG and heart enzymes showed the sign of heart damage. In the chemical therapy period, the treatment group was treated with shenmai and fumei Q10, while the control group with fumei QI0 if the heart damage appeared, both for six cycles. Results The rate of heart damage was 39.6% in 103 AL patients, 9.4% when complete remission（CR）, 21.6% after six therapy cycles, only 12.8 % in treatment group, 31.4% in control group, the difference was significant. Conclusion the rate of heart damage in AL patients decreases as AL relieves and increases after six therapy cycles. Treating mainly with shenmai is an effective way in prevention and treatment.