儿童急性下呼吸道感染肺炎克雷白菌感染状况的研究

The Research for Incidence of Klebsialla Pneumonia Infection in Acute lower Respiratory Infection in Children

目的了解儿童急性下呼吸道感染肺炎克雷白菌(KlebsiallaPneumonia)(KPN)感染状况和特点。方法采用敏感性较好培养方法对288例各年龄组下呼吸道感染住院儿童进行痰培养。结果共发现肺炎克雷白菌(KPN)阳性58例,总感染率(20.14%),其中89例肺炎中,KPN阳性34例(38.21%),128例毛细支气管炎KPN阳性19(14.85%),71例支气管炎KPN阳性5例(7.05%)。结论肺炎克雷白菌(KPN)是儿童急性下呼吸道感染的重要病原,其在儿童急性感染中占有重要地位,在毛细支气管炎,支气管肺炎,支气管炎中作用值得重视。且KPN多产生ESBL,对儿科常用药耐药率高。对亚胺培南,氧哌嗪/他唑巴坦敏感。

Objective To investigate the prevalence and characteristic of Klebsialla Pneumonia （KPN） infection in acute lower respiratory infection . Rethods Sputum were cultured by ralatively sensitive method in 288 inpatients with all kinds of lower respiratory infection in children . Results In total of 288 lower respiratory infection inpatients , 58 （20.14%） were KPN positive . And among the KPN positive cases , 34 （38.21%） Pneumonia , 19 （14.85%） brochiolitis , 5 （7.05%） bronchitis . Conclusion KPN was an important pathogan in children lower respiratoy infection . And KPN plays a major role in acute lower respiratory infection （included brochiolitis , pneumonia , bronchitis）. The role that KPN plays in lower respiratory tract infection deserves to be awared of . Most of KPN produce ESBLS , KPN stains were resistant to common antimicrobials in high degrees. But are susceptible to Menopenemand （Imipenem） and piperacilline /tazobatan .