低分子肝素非注射给药的研究概况
被引量:1
Research status of noninvasive delivery methods for low molecular weight heparin
摘要
目的综述低分子肝素非注射给药的最新研究进展。方法依据近年来国内外相关文献对低分子肝素给药途径与新剂型等方面进行分析、整理和归纳。结果非注射途径给药方式,尤其是口服给药方式是研究的热点。结论低分子肝素的非注射给药开发前景广阔。
出处
《中国生化药物杂志》
CAS
CSCD
2006年第5期310-312,共3页
Chinese Journal of Biochemical Pharmaceutics
参考文献24
-
1Schmitz T,Leitner V M,Bernkop-Schnürch A.Oral heparin delivery:design and in vivo evaluation of a stomach-targeted mucoadhesive delivery system[J].J Pharmac Sci,2005,94(5):966-973.
-
2Mori S,Matsuura A,Rama Prasad Y V,et al.Studies on the intestinal absorption of low molecular weight heparin using saturated fatty acids and their derivatives as an absorption enhancer in rats[J].Biol Pharm Bull,2004,27(3):418-421.
-
3Prasad Y V,Minamimoto T,Yoshikawa Y,et al.In situ intestinal absorption studies on low molecular weight heparin in rats using labrasol as absorption enhancer[J].Int J Pharmac,2004,271(1-2):225-232.
-
4Thanou M,Verhoef J C,Junginger H E.Oral drug absorption enhancement by chitosan and its derivatives[J].Adv Drug Deliver Rev,2001,(52):117-126.
-
5Yang T,Arnold J J,Ahsan F.Tetradecylmaltoside (TDM) enhances in vitro and in vivo intestinal absorption of enoxaparin,a low molecular weight hepari n[J].J Drug Target,2005,13(1):29-38.
-
6Kast C E,Guggi D,Langoth N,et al.Development and in vivo evaluation of an oral delivery system for low molecular weight heparin based on thiolated polycarbophil[J].Pharm Res,2003,20(6):931-936.
-
7Lee Y,Nam J H,Shin H C,et al.Conjugation of low-molecular-weight heparin and deoxycholic acid for the development of a new oral anticoagulant agent[J].Circulation,2001,104(25):3116-3120.
-
8Hoffart V,Ubrich N,Simonin C,et al.Low molecular weight Heparin-loaded polymeric nanoparticles:formulation,characterization,and release characteristics[J].Drug Dev Ind Pharmac,2002,28(9):1091-1099.
-
9Hoffart V,Ubrich N,Lamprecht A,et al.Microencapsulation of low molecular weight heparin into polymeric particlesdesigned with biodegradable and nonbiodegradable polycationic polymers[J].Drug delivery,2003,10 (1):1-7.
-
10Kima S K,Lee E H,Lee Y K,et al.Tricapryl in microemulsion for oral delivery of low molecular weight heparin conjugates[J].J Control Release,2005,105:32-42.
二级参考文献20
-
1崔慧斐,张天民.低抗凝肝素来源低分子肝素口服制剂的研究[J].中国生化药物杂志,1993,14(4):10-15. 被引量:14
-
2张天民,崔慧斐,王凤山,罗振,李华,王福清,杨立波,李素霞,沈渤江.高抗血栓活性的低分子肝素[J].中国医药工业杂志,1994,25(7):301-309. 被引量:38
-
3徐子猷,陈纪岳,李巧云,舒薇,吴怀瑛.甲硝唑明胶海绵阴道栓剂的实验研究[J].中国医院药学杂志,1994,14(9):387-389. 被引量:13
-
4董泽民.赖氨匹林脂质体鼻腔给药的研究[J].中国医药工业杂志,1995,26(5):199-202. 被引量:18
-
5翟光喜,邹立家,张天民.低分子肝素脂质体透皮吸收制剂的研究[J].药物生物技术,1996,3(4):221-223. 被引量:7
-
6王凤山,姬胜利,曹宗顺,张天民.几种生化药物的研究进展及开发方向[J].中国生化药物杂志,1997,18(2):100-103. 被引量:16
-
7罗金德 马竹卿 等.喜树碱多相脂质体(PL-CSA)的研究[J].药学学报,1981,19(1):63-63.
-
8Muramatsu K, Maitani Y, Takayama K, et td. The relationship between the rigidity of the liposomal membrane and the absorption of insulin after nasal administration of liposomes modified with an enhancer containing insulin in rabbits[J]. Drug Dev Ind Pharm , 1999,25(10) :1099-1104.
-
9Cevc G, Schatzlein A, Gabriele B. Transdermal drug carriers: basic properties, optimization and transfer efficiency in the case of epicutaneously applied peptides[J]. J Cont Rel, 1995, 36:3-7.
-
10中国药典.二部,2000年,74页
共引文献19
-
1郭海燕,莫穗林.脂质体物理稳定性和包封率的影响因素[J].中国新药杂志,2004,13(6):498-501. 被引量:37
-
2刘利,王玉芹,张卫东.气相色谱法测定低聚糖类药物中N,N-二甲基甲酰胺的残留量[J].中成药,2006,28(5):703-704.
-
3赵军,王娟,翟光喜.低分子肝素制剂的研究进展[J].食品与药品,2006,8(06A):10-12.
-
4张代平,杨义雄.脂质体制剂的研究概况[J].海峡药学,2006,18(6):21-24. 被引量:7
-
5刘砚韬,陈力,申向黎,张伶俐.鼻腔给药新制剂的研究进展[J].中国药业,2007,16(2):27-28. 被引量:2
-
6冯胜,张毕奎.鼻黏膜给药剂型的研究进展[J].中国药房,2007,18(8):625-627. 被引量:7
-
7李魏娜,刘力,徐德生.药物经呼吸道递送研究进展[J].上海医药,2007,28(4):167-169. 被引量:1
-
8蒋正立,朱萍.纳米脂质体研究新进展[J].海峡药学,2008,20(11):5-7. 被引量:7
-
9李丁,吴闻哲,程志红.低分子肝素非注射给药途径及分析方法研究[J].世界临床药物,2010,31(11):676-681.
-
10鲁卫东,马波,倪俊学,李杰.流感疫苗类脂质体制备及稳定性研究[J].扬州大学学报(农业与生命科学版),2010,31(4):57-59.
同被引文献2
-
1Smith SC Jr,Feldman TE,Hirshfeld JW Jr,et al.ACC/AHA/SCAI 2005 guideline update for percutaneous coronary intervention;a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (ACC/AHA/SCAI Writing Committee to Update 2001 Guidelines for Percutaneous Coronary Intervention).Circulation,2006,113;e166-e286.
-
2Silber S,Albertsson P,Aviles FF,et al.Guidelines for Percutaneous coronary intervention.Eur Heart J,2005,26(8);804-847.
-
1张宇.非注射给药胰岛素的开发[J].国外药讯,2004(5):25-26.
-
2林玳.干扰素的非注射途径给药及临床应用[J].综合临床医学,1997,13(2):115-116. 被引量:2
-
3吴琼珠,平其能.胰岛素非注射给药途径的研究进展[J].解放军药学学报,2000,16(1):28-30. 被引量:13
-
4丁立,孙素珍.胰岛素非注射给药的现状综述[J].药学与临床研究,2007,15(4):264-266. 被引量:2
-
5梁永广,赵秀杰,李明光,李芹.胰岛素口服给药研究概况[J].中国药师,2003,6(1):48-50. 被引量:3
-
6田瑞琴,何应.细胞因子类药物制剂研究进展[J].中国生化药物杂志,2005,26(5):315-317. 被引量:2
-
7徐加夫.胰岛素智能给药系统的研究[J].齐鲁药事,2009,28(7):419-421.
-
8屠婕红.胰岛素非注射制剂的研究概况[J].中国药业,2001,10(12):57-58.
-
9常怡勇,刘爱群.胰岛素非注射给药开发进展[J].中国处方药,2003(8):69-69.
-
10陈军,易以木,杨希雄.胰岛素非注射途径给药系统的研究进展[J].中国药师,2001,4(3):178-179.