壳聚糖及其衍生物与脂肪相互作用的研究

Interactions of Chitosan and Its Derivatives with Fat

以壳聚糖(CTS)及其衍生物为脂肪吸附剂,花生油为吸附对象,通过模拟人体消化系统做体外实验,考察了3种不同性质的壳聚糖衍生物的脂肪吸附容量,其中羟丙基三甲基壳聚糖季铵盐(HTACC)为强阳离子壳聚糖,羧甲基壳聚糖(CMCTS)为亲水性壳聚糖,十六烷基壳聚糖(CTCTS)为疏水性壳聚糖。结果表明:阳离子壳聚糖优于其他衍生物,平均每克可吸附29g油脂;CTCTS次之,每克吸附25g;CTS可吸附22g;CMCTS最差,仅为16g。以壳聚糖和阳离子衍生物为例,进一步考察了影响壳聚糖吸附脂肪的因素,研究表明:作为溶剂的盐酸溶液的pH和用量均可影响样品的吸脂能力,当样品-盐酸溶液浓度为0.01 g/mL、pH为2时,吸附效果较好。

Chitosan（CTS）, N-hydroxy propyl three methyls ammonium chloride chitosan（HTACC）ot cationic chitosan derivative, carhoxymethyl chitosan（CMCTS）of hydrophilic chitosan derivative and hydrophobe cetyl-chitosan （CTCTS） were used to interacte with peanut oil in vitro by using a model of digestive tract in order to inves- tigate their fat-binding capacity（FBC） .The result indicated that the FBC was 22 g, 29 g, 25 g and 16 g for CTS, HTACC, CTCTS and CMCTS respectively. The effects of pH and the volume of hydrochloricacid water solution used on the fat-binding capacity were also important. When hydrochloricaci acid water solution concentration was 0.01 g/mL and pH = 2, the FBC reached to the maximum.