癫疒间患者抑郁障碍发生率及相关因素调查

Investigation of incidence and risk factors for depression in patients with epilepsy

目的:探讨癫疒间患者抑郁发生率和相关危险因素。方法:运用自制问卷对患者的个人及家庭一般情况进行调查记录,采用Zung抑郁自评量表对104例癫疒间患者进行筛选、抑郁评定,并对不同因素对癫疒间患者抑郁发病率的影响进行比较。结果:104例癫疒间患者中有55例52.9%合并有抑郁症状,其中37例(35.6%)有严重抑郁,8例(17.3%)为中、轻度抑郁。复杂性部分发作患者抑郁的患病率为73.5%,明显高于强制-阵挛发作的42.8%,两者差别有统计学意义(P<0.01)。结论:癫疒间患者的抑郁是严重的医疗和社会问题其发生与癫疒间发作的类型,频率病程和社会家庭的支持有关。

Objective To study the incidence of depression and determine the major depression risk factors in patients with epilepsy. Methods One hundred and four patients with epilepsy were evaluated with Zung＇s self rating depression scale. A self-designed questionnaire was used in this investigation for general conditions of the patients. Results In our study 55 patients with epilepsy suffered from concurrent depression （52. 9%）,in which 37 had severe depression （35. 6%） and 18 patients had mild depression （17.3%）. The incidence of depression in complex partial seizures group was 73.5% ,which showed evident statistic difference changes compared with 42.8% of generalized tonic-clonic seizures. Conclusion Depression in patients with epilepsy is a serious medical and social problem. It seems to be correlated with certain types of epileptic seizures, with high frequency of seizures, course of disease, and lack of support from family and society.